Immunestimulatory and therapeutic activity of tinospora. It works because pathogens cannot mutate to avoid the antimicrobial. Antimicrobial activity of crude aqueous extracts of moringa oleifera, azadirachta indica, carica papaya, tinospora cordifolia and curcuma longa against certain bacterial pathogens june 2018. Methods to determine antimicrobial activity 1yazan ismail, 2mohammed wedyan, 1muad alzuabe and 2salim abderrahman 1department of allied medical. Tinospora cordifolia was shown to possess cytotoxic activity against human breast cancer cells. Tinospora cordifolia an overview sciencedirect topics. Tinospora cordifolia possess very good antibacterial activity which makes them a potent source of antibacterial agent. The extraction of alkaloid palmatine from tinospora cordifolia by using response. The antibacterial activity of the hydroalcoholic extracts of tinospora cordifolia was determined by agarwell diffusion method. The common names are amrita and guduchi and belong to the. Tinospora cordifolia is one of the constituents of several ayurvedic preparations used in general debility, dyspepsia, fever and urinary. The antimicrobial activity was determined by measuring the diameter of zone of inhibition. Original article in vitro study of antimicrobial activity.
Antifungal and phytochemical properties of tinospora. The antimicrobial activity of silver nanoparticles synthesized from leaves and stem of tinospora cordifolia. Introduction among plants of economic importance, medicinal and aromatic plants have played a. Ic50 values of tc methanolic extract with respect to mdamb231 were. The results confirmed that tinospora cordifolia is a rich reservoir of endophytic bacteria which are good source of biologically active compounds responsible for antimicrobial activity. Materials and methods plant collection and authentification. An in vitro study was undertaken in which extract of t. A study of antimicrobial activity of few medicinal herbs parastoo karimi alavijeh, parisa karimi alavijeh and devindra sharma. The antimicrobial activity of tc stem extracts was. The hydroalcoholic extract of tinospora cordifolia have been reported to be rich in flavonoids, alkaloids and glycosides 11 and has been shown to exhibit antibacterial property against certain. Issn 23203862 evaluation of anticancer activity of stem. View tinospora cordifolia research papers on academia.
The study was performed to check the chemical, antioxidant, antimicrobial and protein binding qualities of the hydroethanolic extract of tinospora cordifolia tc. It has been traditionally used for treatment of diabetes, jaundice, chronic diarrhoea, cancer, dermatological diseases, general debility, and asthma. Miers plant extracts against selected clinical isolates mamta devi, anchal sharma, navdeep, sudhir saroea. The methanolic extract would be studied further for isolation and characterization of active components for lead optimization studies. Based on ethno pharmacological and taxonomic information, antimicrobial activities of crude aqueous extracts of five medicinal plants including leaves of moringa oleifera, azadirachta indica. Results of antimicrobial activity revealed that these. Viola species and tinospora cordifolia as herbal antibiotics. A study of antimicrobial activity of few medicinal herbs. There were only limited studies done on both hydrophilic and hydrophobic extracts of a. Review of biological activities of tinospora cordifolia abstract.
Introduction i t is the need of hour to show the effectiveness of the drug in a disease by laboratory findings. In vitro antibacterial effect of tinospora cordifolia. Four different solvents ethyl acetate, chloroform, diethyl ether and aqueous were used to obtain extracts of bacterial endophytes for qualitative phytochemical analysis. Azadiracta indica, acacia nilotica, tinospora cordifolia. Evaluation of antimicrobial activity and phytochemical. Methanolic extract of tinospora cordifolia showed significant anticancer activity against mdamb231 human breast cancer cell line. Phenylpropanoid glycosides and tetrahydrofuranlignan glycosides from the adaptogenic plant drugs tinospora cordifolia and drypetes roxburghii. Anticancer, cytotoxicity, invitro, mdamb231, breast cancer, tinospora cordifolia 1. Antibacterial properties of biologically synthesized. Scientific validation of the medicinal efficacy of. Tinospora cordifolia guduchi, a reservoir plant for.
The treatment of infectious diseases with antimicrobial agents continues to present problems in modernday. Lysozymes act as a potent antimicrobial compound against grampositive species shimada et al. Therefore antimicrobial silver is now used extensively to combat organisms in wounds and burns. Tinospora cordifolia, which is known by the common names heartleaved moonseed, gaduchi, and giloya, is an herbaceous vine of the family menispermaceae indigenous to the tropical areas of. Review of biological activities of tinospora cordifolia. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of tinospora. Antifungal activity of various extract of leaves of tinospora cordifolia, azadirachta indica and ocimum sanctum would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin.
Acorus calamus sweet flag is a wellknown traditional herb used in india. Antibacterial activity of tinospora cordifolia request pdf. The amount of lysozymes that leads to microbial activation of macrophages was found to be higher on treatment with t. The present study was aimed at determining the activity of aqueous and methanolic extracts of tinospora cordifolia aetc and metc against salmonella typhimurium. Tinospora cordifolia chemical constituents and medicinal. Tinospora cordifolia is a popular medicinal plant which is used in several traditional medicines to cure various diseases. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of tinospora crispa stems extracted using soxhlet extraction method. Pdf antimicrobial activity of crude aqueous extracts of. In addition, plants also have antimicrobial agents to inhibit the growth of pathogenic microbes. Antibacterial activity of aqueous, ethanol and chloroform extracts of leaves and stem of tinospora cordifolia hook. Anticancer activity tinospora cordifolia shows anticancer activity, this activity is mostly shown in animal models.
Evaluation of antimicrobial activity and phytochemical screening of extracts oftinospora cordifolia against some pathogenic microbes dinesh bansal 1, pragya bhasin, anita punia1, and anita r. Antioxidant and antibacterial activity of acorus calamus. The present study aimed to assess the antimicrobial activity of different concentrations of commercially available t. Tinospora cordifolia guduchi or amrita is an important drug of ayurvedic system of medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes. The antimicrobial property of tinospora cordifolia has been tested against a variety of microorganisms in the literature. Tinospora cordifolia is an important herb of tropical india in ayurvedic system of medicines. Tinospora cordifolia, antioxidant activity, medicinal plant, antihyperglycemic activity. The antimicrobial activities of tinospora cordifolia leaf extracts are compared with standard antibiotics such as amoxicillin, which was used as positive controls.
The isolated bacterial were first cultured in a nutrient broth. Research article screening of antimicrobial activity of. The silver ions, as well as silver nanoparticles, were known to have strong antimicrobial activities 2427. Tinospora cordifolia leaf extracts and investigation of their antibacterial effects for the first time. The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, tinospora cordifolia and euphorbia hirta those are commonly available in india. The purpose of this study was to evaluate the antimicrobial effect of rubia cordifolia root water and methanol extracts on various microorganisms using the agar well diffusion method and to. Tinospora cordifolia m enispermaceae, matured stems was collected locally at thanjavur. Antimicrobial susceptibility assay of tinospora cordifolia leaf extract table 2 antimicrobial susceptibility assay of tinospora cordifolia stem extract sr. The antibacterial activity of tinospora cordifoliaextracts has been assayed against various gram positive and gram negative organisms.
Antioxidant and antimicrobial properties of tinospora. Present communication reports the scientific evaluation of tinospora cordifolia for its medicinal efficacy which includes phytochemical screening, antimicrobial, antioxidant, and anticancer activities. Comparative antimicrobial activity of ethanolic and. Thoms were tested on clinical isolates of urinary pathogens viz. Antimicrobial activity of some medicinal plants from india. Antimicrobial activity, guduchi, guduchi ghana, physicochemical, tinospora cordifolia. Tinospora cordifolia belonging to the family menispermaceae.
Preliminary phytochemical screening and evaluation of free radical scavenging activity of tinospora cordifolia. The results of a preliminary antimicrobial screening of the methanol extracts of zingiber officinale, asteracantha longifolia, citrus acida, salacia microsperma and tinospora cordifolia are reported. The zones of inhibition in diameter cm recorded for ethanol, chloroform and aqueous are depicted in table 1. It is revealed that the ethanolic extracts exhibited significant antibacterial activity against proteus vulgaris, escherichia coli and moderate activity. The chemical constituents and diverse pharmacological. Antimicrobial efficiency of tinospora cordifolia and hymenocallis littoralis, medicinal plants were examined using ethanol, methanol, chloroform, dichloromethane, ethyl acetate as solvents a nd found that all the plants parts showed significant activity against all pathogens. Studies on in vitro antibacterial activity of tinospora. Antibacterial properties of biologically synthesized chitosan nanoparticles along with leaves extract. The aim of the present study was to evaluate the antimicrobial activity of tinospora cordifolia extracts against three standard atcc strains of escherichia coli, staphylococcus aureus and. Phytochemical, antioxidant, antimicrobial, and protein. Mahesh et al 20085 carried out antimicrobial activity of some important medicinal plant against plant and human pathogens on the methanol leaf extracts of acacia nilotica, sida cordifolia, tinospora cordifolia,withania somnifera and ziziphus mauritiana showed significant antibacterial activity. In vitro antimicrobial activity of tinospora cordifolia.
935 1391 1285 1011 893 525 505 522 6 787 1152 1350 462 1254 1606 2 1559 1175 437 254 1164 721 1005 286 1329 403 1384 1181 8 1444 1377 747